MSU receives 5 million NIH grant to find link between pesticides and

first_img Source:https://msutoday.msu.edu/news/2019/msu-lands-5m-nih-grant-to-connect-dots-between-pesticides-and-parkinsons/ Reviewed by James Ives, M.Psych. (Editor)Mar 6 2019A Michigan State University researcher is hoping to make a connection between pesticides, olfactory impairment and early symptoms of neurodegenerative diseases among aging farmers.Honglei Chen, a professor of epidemiology whose research focuses on neurodegenerative diseases, will use a five-year, $5 million grant from the National Institutes for Health to investigate the role pesticides might play in olfactory impairment and their relevance to diseases such as Alzheimer’s and Parkinson’s.Related StoriesComplement system shown to remove dead cells in retinitis pigmentosa, contradicting previous researchBridging the Gaps to Advance Research in the Cannabis IndustryAXT enhances cellular research product portfolio with solutions from StemBioSys”Our battle against Alzheimer’s and Parkinson’s may depend on early disease identification and intervention, and poor olfaction has been identified as an early warning for these diseases,” Chen said. “This grant will allow us to connect the dots by identifying factors that contribute to poor olfaction among older adults and evaluating how this sensory deficit may progress to early stages of neurodegenerative diseases.”In preliminary analyses, researchers found a correlation between high pesticide exposure and self-reported poor sense of smell. In this project, researchers will objectively assess the olfaction of around 2,200 farmers using a standard smell test.Using a scratch-and-sniff method, participants will need to correctly identify 12 common smells such as smoke, lemon, cinnamon or gasoline. Researchers will then conduct home visits of approximately 450 farmers to assess cognitive function and motor symptoms.”We are trying to put everything into context with the ultimate goal of understanding the early stages of neurodegenerative diseases and factors involved,” Chen said. “This project focuses on pesticides because earlier studies show their potential connections to neurodegenerative diseases. Now we want to define what role they play.”last_img read more

New model for intensive care identifies factors that send ill patients to

first_img Source:https://news.rutgers.edu/new-model-icu-care-developed-rutgers-discovers-causes-health-emergencies/20190315#.XJMzASIzbct Reviewed by James Ives, M.Psych. (Editor)Mar 21 2019A new model for intensive care, developed by Rutgers and RWJBarnabas Health System, can help identify preventable – and previously overlooked – factors that often send chronically ill patients to the intensive care unit (ICU).The new process requires the ICU team – including physicians, nurses, pharmacists, social workers, chaplains and others – to truly listen to patients and their families to ensure their needs are being met, according to a recent study in the journal Creative Nursing.The new model, called LOTUS (Leadership, Ownership, Transformation, Unity and Sustainability) differs significantly from the previous model in which all planning was led by the ICU physician, said lead researcher Liza Barbarello Andrews, a clinical associate professor at Rutgers’ Ernest Mario School of Pharmacy and critical care pharmacy specialist at Robert Wood Johnson University Hospital.During its first year, the new patient-focused model identified areas where the ICU was not routinely assessing the causes of the health crises that sent patients to the hospital in the first place – missing opportunities to break the cycle of admissions, Andrews said.”Many patients present with life-threatening complications due to failure to take their diabetes or blood pressure medications,” he said. “We would treat the resulting problem, but hadn’t been routinely investigating what led to the issue or designed a solution to prevent it from happening again in the future. Under the LOTUS model, by focusing on the patient perspective we discovered that some patients had received confusing, mixed messages about the medicine from their health-care providers. Other patients were struggling with financial or emotional problems that made self-care difficult.”Related StoriesStudy analyzes high capacity of A. baumannii to persist on various surfacesFeeling safe and good sleep at night matter most to sick kids in hospitalRaw meat can act as reservoir for bacteria associated with hospital infectionsThe LOTUS model empowers ICU social workers to help address those issues with patients and their families to prevent a reoccurrence.Clinicians developed LOTUS at Robert Wood Johnson University Hospital Hamilton, following its 2016 merger with RWJBarnabas Health System. The new ICU model replaced an earlier one where patient care decisions were exclusively led by the ICU physician without routine focus on the patient’s own goals or significant input from nurses, pharmacists and other members of the ICU team.Under the old model, there was no formal structure for rounds, the practice where all members of the ICU team assess the patient at intake and through treatment. This lack of standard team structure often resulted in underutilizing individual team members’ expertise.The new illustrative logo for the ICU model is a flower with the patient at the center and the petals – the members of the health care team – overlapping and meeting at the center.”We took a model that was fragmented and sometimes strayed from keeping the patients’ own wishes central to the decision-making process – and developed one that is much more efficient, thoughtful and deliberative,” Andrews said. “The ICU team members feel a real sense of engagement and collaboration and patients and families say they feel listened to.ICU team members said the LOTUS model helped them contribute to better patient safety, decreased mortality and shorter ICU stays. Members of other teams at RWJBarnabas Health System campuses are exploring how the LOTUS concept can be adopted for their ICU teams.last_img read more

Elite NKorean hacker group tied to bank attacks researchers

first_img Explore further An elite group of North Korean hackers has been identified as the source of a wave of cyberattacks on global banks that has netted “hundreds of millions” of dollars, security researchers said Wednesday. Cybersecurity firm: More Iran hacks as US sanctions loomed A report by the cybersecurity firm FireEye said the newly identified group dubbed APT38 is distinct from but linked to other North Korean hacking operations, and has the mission of raising funds for the isolated Pyongyang regime.FireEye researchers said APT38 is one of several hacking cells within an umbrella group known as “Lazarus,” but with unique skills and tools that have helped it carry out some of the world’s largest cyber heists.”They are a cybercriminal group with the skills of a cyberespionage campaign,” said Sandra Joyce, FireEye’s vice president of intelligence, in a briefing with journalists in Washington.Joyce said one of the characteristics of APT38 is that it takes several months, sometimes nearly two years, to penetrate and learn the workings of its targets before its attacks, which have sought to illegally transfer more than $1 billion from victimized banks.”They take their time to learn the intricacies of the organization,” Joyce said.Once they succeed, she added, “they deploy destructive malware on their way out” to hide their traces and make it more difficult for victims to find out what happened.Sense of urgencyJoyce said FireEye decided to go public about the threat out of a “sense of urgency” because the group appears to still be operating and is “undeterred by any diplomatic efforts.”The group has compromised more than 16 organizations in at least 11 different countries since at least 2014, according to the FireEye report. Some of the known attacks have targeted the Vietnam TP Bank in 2015, Bangladesh Bank in 2016, Far Eastern International Bank of Taiwan in 2017 and Bancomext of Mexico and Banco de Chile in 2018.Joyce said the group appears to have “the scope and resources of a nation-state” but offered no specific figures on how many people it uses. Security researchers say an elite group of North Korean hackers has stolen hundreds of millions of dollars from banks worldwide © 2018 AFP Focused missionSome of the information about APT38 was revealed in a US criminal complaint unsealed last month against Park Jin Hyok, charged in connection with WannaCry ransomware outbreak and the attack on Sony Pictures.But Park likely played only a peripheral role in APT38,which “has a focused mission to steal money to fund the North Korean regime,” according to Joyce.FireEye’s new report was based in part on forensic analysis it conducted for the FBI in the investigation into Park, but also from other data the security firm has gathered from its global client base.The researchers said APT38 used techniques including “phishing” emails to gain access to credentials and using “watering holes”—hijacked websites that appear normal but which contain malware that enable hackers to gather more data and access.As part of the scheme, the hackers created fake identities within known nongovernmental organizations or foundations to help move the stolen money, in some cases manipulating the global interbank transfer system known as SWIFT.The report is the latest highlighting a vast and increasingly sophisticated cyber campaign by North Korea for both political and financial ends.In September, a 176-page criminal complaint against Park outlined what officials called “a vast and audacious scheme by the North Korean government to utilize computer intrusions as a means to support the varied goals of their regime.”On Tuesday, the US Department of Homeland Security warned that North Korea is likely behind malware used to hack into and steal money from bank teller machines.The bulletin said officials believe the “Hidden Cobra” malware enabled North Korea to illegally get cash from bank machines in at least 30 countries, mainly in Asia and Africa, since 2016. Researchers said that North Korean national Park Jin Hyok, who was named in a US criminal complaint last month unveiled by Justice Department officials at a news conference pictured here, was peripherally involved in an elite bank hacking operation This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only. Citation: Elite N.Korean hacker group tied to bank attacks: researchers (2018, October 3) retrieved 17 July 2019 from https://phys.org/news/2018-10-elite-nkorean-hacker-group-tied.html Nalani Fraser, a member of the FireEye research team, said APT38 attacks sought at least $1.1 billion since 2014 and have managed to steal “hundreds of millions of dollars based on data that we can confirm.”FireEye said there appears to be some sharing of resources between hacker groups in North Korea, including those involved in espionage and those in other kinds of attacks.last_img read more

Karnataka should handle its coal stocks more efficiently says GoyalKarnataka should handle

first_imgCOMMENTS ‘Rising imports, coal shortage are key challenges for the aluminium sector’ December 27, 2018 RELATED ‘India can meet 300 mtpa steel production target by 2030’ SHARE SHARE EMAIL There is no shortage of coal in Karnataka, according to Minister of Coal and Railways, Piyush Goyal.In a statement issued after a meeting with former Prime Minister HD Deve Gowda and Chief Minister of Karnataka HD Kumaraswamy, Goyal said there is no scarcity of coal in the State. He also said that the plants in Karnataka currently have, on an average, five days stock of coal which is equal to 2.24 lakh tonnes.Goyal hit out at the Karnataka government and hinted at mismanagement of coal stocks. “Karnataka Power Corporation Ltd. (KPCL) sold 584.91 million units of power at the energy exchange this year till October 2018. This amounts to consuming 3.8 lakh tonnes of coal which otherwise could have been used to boost coal stocks in power plants,” he said.“It is better that the plants maintained at least 20 days’ stock of coal for uninterrupted functioning,” he added. He pointed to the anticipated pick-up in the demand for power in February/March 2019 and asked the power plants to manage their inventory efficiently. Peak in demandHe said that transaction at energy exchanges should be done to take advantage of cheaper power right now to ensure better build up of coal stocks in thermal power plants. “This will help avoid purchase of power in February/March, when prices are expected to be higher due to peaking of demand,” he added.center_img coal Published on SHARE COMMENT Piyush Goyal, Interim Finance Minister   –  BusinessLinelast_img read more

Classy Djokovic charges into another Wimbledon final

first_img Related News Related News Tennis 10 Jul 2019 Ibiza party on hold as Bautista Agut reaches Wimbledon semis Tennis 10 Jul 2019 Highlights: Wimbledon day nine “He played really well. He was managing his nerves in the first set but later on he established himself and started to play better. I got a bit tight. It was a close opening four or five games of the third set – that’s where the match could have gone a different way.”Bautista Agut flashed a brilliant return past Djokovic from the first serve of the match but he barely threatened for the rest of the set as his high-risk approach produced too many errors and a provided a straightforward set win for the favourite.The second was a different story as Bautista Agut dialled back a little and found that he was able to out-duel the master. Djokovic was making uncharacteristic errors on seemingly simple shots and was frequently left staring skywards, questioning himself and taking issue with the crowd.Bautista Agut snatched a break in the third game and served superbly to back it up, dropping only four points in five successful service games to level the match.REAL MATCHThe Centre Court crowd realised they had a real match on their hands and they were treated to a superb third set. It, and probably the match, hinged on the seventh game as Djokovic, a break to the good, served at 30-40.The players then smashed out their 45-shot rally, much of it a mesmerizing exchange of identical crosscourt backhands that had the crowd gasping before Djokovic blinked first to switch the angle of attack and take the point with a devastating winner.It was the longest rally officially seen at Wimbledon since records began in 2005 and Djokovic duly served out and stayed on top to take the set.The champion then took command in the fourth set, cutting out the loose groundstrokes and picking up points with adventurous serve-and-volley attacks and after breaking for a 2-1 lead he never looked back.”Obviously winning that game was crucial for me,” Djokovic said of the marathon rally game. “It gave me more confidence and relief so I could swing more freely in the next games.”Bautista Agut had no answers but can be pleased with his efforts in what is turning out to be the best year of his career, having never previously reached even a quarter-final at a Grand Slam.The 31-year-old can now join his friends on a belated stag break. They arrived in London to watch Friday’s game after his planned Ibiza trip was cancelled following his unexpected progress to the last four.Djokovic, however, has got more business to attend to as he prepares to face 37-year-old eight-times Wimbledon champion and number two seed Federer in Sunday’s showpiece.”Regardless of the history and many finals I’ve played, playing a final at Wimbledon is something different so I’ll definitely enjoy that experience,” he said. (Reporting by Mitch Phillips, editing by Ken Ferris)center_img {{category}} {{time}} {{title}} LONDON (Reuters) – Top seed and defending champion Novak Djokovic held off a spirited challenge from Spanish outsider Roberto Bautista Agut on Friday to triumph in four sets and advance to a mouthwatering Wimbledon final against Roger Federer.Remarkably the Serb’s 6-2 4-6 6-3 6-2 success was the 12th victory in his last 13 Grand Slam semi-finals and he is now one win away from his fifth title at Wimbledon and 16th Grand Slam singles crown as he resumes his great rivalry with the Swiss.Friday’s match turned on an amazing 45-shot rally in the seventh game of the third set, which Djokovic won to hold serve and stay a break up – and from then on he took total control as the Spaniard, who had looked calm and confident in his first Grand Slam semi-final, was eventually brushed aside.”I had to dig deep. It’s the semi-finals and Roberto was not overwhelmed – he’s a very under-rated player,” Djokovic, 32, said. Tennis 10 Jul 2019 Clinical Djokovic destroys Goffin to reach semislast_img read more

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Akonanya who offered to give me free legal services. now the executive director of the Cuyuna Lakes Mountain Bike Crew. You people (media) please do not push, Prosecution counsel, the right to directly elect Hong Kongs top official, I went online looking for ideas of what I could do." Green said. “We are bracing for worst and preparing for the worst.A Canadian Psychiatrist who thinks that homosexuality is an illness has been struck off after it emerged that he sexually abused two of his male patients Dr Mervyn Iscove 72 has been found guilty by a disciplinary committee of the College of Physicians and Surgeons of Ontario and lost his licence to practiceSo-called gay conversion therapy is banned in the state of Ontario and the World Health Organisation removed homosexuality from the list of mental illnesses in 1992 Dr Iscove was found to have engaged in anal intercourse with one student as well as engaging in mutual masturbation and oral sex with both of the complainants The doctor denies all of the charges against him and a penalty hearing will now take place Licences are immediately suspended during a penalty hearingCredit: PA Iscoves lawyer Alfred Kwinter told the Toronto Star: "Were both very disappointed with the result obviously "Dr Iscove has always denied the allegations he continues to do so and hes seriously considering an appeal" The committee that ruled on the case said: "Neither complainant described any emotional or romantic aspects of the sexual activity with Dr Iscove and both said that at some point they thought that the sexual activity was part of the therapy and an attempt to cure them of homosexuality by engaging in the acts rather than fantasizing about them" Iscove was found to subscribe to the beliefs about homosexuals held by Dr Edmund Berger Several passages of Bergers work were read at the panel including: "All attempts to prove homosexuality to be anything but an illness had in my opinion failed" and "there are no happy homosexuals" The panels ruling also argued that Iscove: "Soften the effect of these passages but in the end endorsed or at least accepted them" They continued: "Dr Iscove also became evasive in responding to questions as to whether homosexuality should be considered an illness and whether it was capable of being cured despite that these views were clearly held by Dr Bergler" "Given that Dr Iscove had admittedly devoted his professional life to studying and applying the theories of Dr Bergler it was not clear to the committee why Dr Iscove refused to acknowledge that he agreed with Dr Bergler on these points"Credit: PA "The sexual activity subsequently progressed to Dr Iscove removing his penis from his trousers then Patient A doing the same "This progressed on later occasions to mutual masturbation and oral sex Patient A estimated that such activity occurred on between 10 and 20 occasions with oral sex occurring on one-third of the episodes" Due to the nature of the allegations both patients have been granted anonymity Featured Image Credit: PA Topics: News N. findings it has made.

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