MSU receives 5 million NIH grant to find link between pesticides and

first_img Source:https://msutoday.msu.edu/news/2019/msu-lands-5m-nih-grant-to-connect-dots-between-pesticides-and-parkinsons/ Reviewed by James Ives, M.Psych. (Editor)Mar 6 2019A Michigan State University researcher is hoping to make a connection between pesticides, olfactory impairment and early symptoms of neurodegenerative diseases among aging farmers.Honglei Chen, a professor of epidemiology whose research focuses on neurodegenerative diseases, will use a five-year, $5 million grant from the National Institutes for Health to investigate the role pesticides might play in olfactory impairment and their relevance to diseases such as Alzheimer’s and Parkinson’s.Related StoriesComplement system shown to remove dead cells in retinitis pigmentosa, contradicting previous researchBridging the Gaps to Advance Research in the Cannabis IndustryAXT enhances cellular research product portfolio with solutions from StemBioSys”Our battle against Alzheimer’s and Parkinson’s may depend on early disease identification and intervention, and poor olfaction has been identified as an early warning for these diseases,” Chen said. “This grant will allow us to connect the dots by identifying factors that contribute to poor olfaction among older adults and evaluating how this sensory deficit may progress to early stages of neurodegenerative diseases.”In preliminary analyses, researchers found a correlation between high pesticide exposure and self-reported poor sense of smell. In this project, researchers will objectively assess the olfaction of around 2,200 farmers using a standard smell test.Using a scratch-and-sniff method, participants will need to correctly identify 12 common smells such as smoke, lemon, cinnamon or gasoline. Researchers will then conduct home visits of approximately 450 farmers to assess cognitive function and motor symptoms.”We are trying to put everything into context with the ultimate goal of understanding the early stages of neurodegenerative diseases and factors involved,” Chen said. “This project focuses on pesticides because earlier studies show their potential connections to neurodegenerative diseases. Now we want to define what role they play.”last_img read more

New model for intensive care identifies factors that send ill patients to

first_img Source:https://news.rutgers.edu/new-model-icu-care-developed-rutgers-discovers-causes-health-emergencies/20190315#.XJMzASIzbct Reviewed by James Ives, M.Psych. (Editor)Mar 21 2019A new model for intensive care, developed by Rutgers and RWJBarnabas Health System, can help identify preventable – and previously overlooked – factors that often send chronically ill patients to the intensive care unit (ICU).The new process requires the ICU team – including physicians, nurses, pharmacists, social workers, chaplains and others – to truly listen to patients and their families to ensure their needs are being met, according to a recent study in the journal Creative Nursing.The new model, called LOTUS (Leadership, Ownership, Transformation, Unity and Sustainability) differs significantly from the previous model in which all planning was led by the ICU physician, said lead researcher Liza Barbarello Andrews, a clinical associate professor at Rutgers’ Ernest Mario School of Pharmacy and critical care pharmacy specialist at Robert Wood Johnson University Hospital.During its first year, the new patient-focused model identified areas where the ICU was not routinely assessing the causes of the health crises that sent patients to the hospital in the first place – missing opportunities to break the cycle of admissions, Andrews said.”Many patients present with life-threatening complications due to failure to take their diabetes or blood pressure medications,” he said. “We would treat the resulting problem, but hadn’t been routinely investigating what led to the issue or designed a solution to prevent it from happening again in the future. Under the LOTUS model, by focusing on the patient perspective we discovered that some patients had received confusing, mixed messages about the medicine from their health-care providers. Other patients were struggling with financial or emotional problems that made self-care difficult.”Related StoriesStudy analyzes high capacity of A. baumannii to persist on various surfacesFeeling safe and good sleep at night matter most to sick kids in hospitalRaw meat can act as reservoir for bacteria associated with hospital infectionsThe LOTUS model empowers ICU social workers to help address those issues with patients and their families to prevent a reoccurrence.Clinicians developed LOTUS at Robert Wood Johnson University Hospital Hamilton, following its 2016 merger with RWJBarnabas Health System. The new ICU model replaced an earlier one where patient care decisions were exclusively led by the ICU physician without routine focus on the patient’s own goals or significant input from nurses, pharmacists and other members of the ICU team.Under the old model, there was no formal structure for rounds, the practice where all members of the ICU team assess the patient at intake and through treatment. This lack of standard team structure often resulted in underutilizing individual team members’ expertise.The new illustrative logo for the ICU model is a flower with the patient at the center and the petals – the members of the health care team – overlapping and meeting at the center.”We took a model that was fragmented and sometimes strayed from keeping the patients’ own wishes central to the decision-making process – and developed one that is much more efficient, thoughtful and deliberative,” Andrews said. “The ICU team members feel a real sense of engagement and collaboration and patients and families say they feel listened to.ICU team members said the LOTUS model helped them contribute to better patient safety, decreased mortality and shorter ICU stays. Members of other teams at RWJBarnabas Health System campuses are exploring how the LOTUS concept can be adopted for their ICU teams.last_img read more

Maxcure in tieup with Swedenbased Medicover plans expansion

first_imgSHARE SHARE EMAIL February 11, 2019 Maxcure Hospitals, with 51 per cent equity investor, Medicover, the Sweden-based healthcare and diagnostic major, has charted a growth plan focussed on Maharashtra, Chhattisgarh and the two Telugu states.The expansion, which began in 2017 with the dilution of 51 per cent for about Rs 320 crore from the holding company, Sahrudaya Healthcare Pvt Ltd, has already seen Maxcure rapidly scale up its presence from 200 beds in 2015 to 2,000 beds at present. It has 11 multi-speciality hospitals, mostly in Telangana and Andhra Pradesh, said G Anil Krishna, Managing Director.A large part of the growth will be met with funds raised from the investor, internal accruals and, going forward, from debt says Anil, whose vision it is to take the group to the top five in the country’s healthcare sector by 2025. “We are betting big on Maharashtra and Chhattisgarh in the next three years. Navi Mumbai, Aurangabad, Nagpur, and later, Pune, are the prime locations”, he told BusinessLine.Maxcure, which began in 2014 in Hyderabad under the Sahrudaya Healthcare Group and soon took over Mediciti hospitals, has moved into Nashik with a 300-bedded facility and is close to completing a similar sized one in Navi Mumbai. The strategy would be to take high quality, affordable healthcare to tier-2 and 3 cities, he added.The turnover for fiscal 2017-18 was Rs 421 crore and it had done Rs 400 crore by January-end in the current fiscal. Its overall investments have also risen to Rs 500 crore. While each hospital will be a multi-speciality facility with the best medical, para medical and diagnostic care, at two places — Madhapur in Hyderabad and Nellore in Andhra Pradesh — exclusive oncology (cancer) facilities and treatment are also being established, he said.In addition, Medicover has diagnostic facilities in Bengaluru and Mysuru. It has announced its intention to expand its presence in fertility services too. After entering India in 2016 with an agreement to manage the operations of Medicover Fertility India, it has acquired the main shareholder, Medicover Healthcare, Delhi. It has since opened facilities in five cities, with the latest being in Hyderabad. Published on Growth plans to focus on Maharashtra, Chhattisgarh, Telangana, Andhra Pradesh COMMENTS 0 SHARE COMMENTlast_img read more

Classy Djokovic charges into another Wimbledon final

first_img Related News Related News Tennis 10 Jul 2019 Ibiza party on hold as Bautista Agut reaches Wimbledon semis Tennis 10 Jul 2019 Highlights: Wimbledon day nine “He played really well. He was managing his nerves in the first set but later on he established himself and started to play better. I got a bit tight. It was a close opening four or five games of the third set – that’s where the match could have gone a different way.”Bautista Agut flashed a brilliant return past Djokovic from the first serve of the match but he barely threatened for the rest of the set as his high-risk approach produced too many errors and a provided a straightforward set win for the favourite.The second was a different story as Bautista Agut dialled back a little and found that he was able to out-duel the master. Djokovic was making uncharacteristic errors on seemingly simple shots and was frequently left staring skywards, questioning himself and taking issue with the crowd.Bautista Agut snatched a break in the third game and served superbly to back it up, dropping only four points in five successful service games to level the match.REAL MATCHThe Centre Court crowd realised they had a real match on their hands and they were treated to a superb third set. It, and probably the match, hinged on the seventh game as Djokovic, a break to the good, served at 30-40.The players then smashed out their 45-shot rally, much of it a mesmerizing exchange of identical crosscourt backhands that had the crowd gasping before Djokovic blinked first to switch the angle of attack and take the point with a devastating winner.It was the longest rally officially seen at Wimbledon since records began in 2005 and Djokovic duly served out and stayed on top to take the set.The champion then took command in the fourth set, cutting out the loose groundstrokes and picking up points with adventurous serve-and-volley attacks and after breaking for a 2-1 lead he never looked back.”Obviously winning that game was crucial for me,” Djokovic said of the marathon rally game. “It gave me more confidence and relief so I could swing more freely in the next games.”Bautista Agut had no answers but can be pleased with his efforts in what is turning out to be the best year of his career, having never previously reached even a quarter-final at a Grand Slam.The 31-year-old can now join his friends on a belated stag break. They arrived in London to watch Friday’s game after his planned Ibiza trip was cancelled following his unexpected progress to the last four.Djokovic, however, has got more business to attend to as he prepares to face 37-year-old eight-times Wimbledon champion and number two seed Federer in Sunday’s showpiece.”Regardless of the history and many finals I’ve played, playing a final at Wimbledon is something different so I’ll definitely enjoy that experience,” he said. (Reporting by Mitch Phillips, editing by Ken Ferris)center_img {{category}} {{time}} {{title}} LONDON (Reuters) – Top seed and defending champion Novak Djokovic held off a spirited challenge from Spanish outsider Roberto Bautista Agut on Friday to triumph in four sets and advance to a mouthwatering Wimbledon final against Roger Federer.Remarkably the Serb’s 6-2 4-6 6-3 6-2 success was the 12th victory in his last 13 Grand Slam semi-finals and he is now one win away from his fifth title at Wimbledon and 16th Grand Slam singles crown as he resumes his great rivalry with the Swiss.Friday’s match turned on an amazing 45-shot rally in the seventh game of the third set, which Djokovic won to hold serve and stay a break up – and from then on he took total control as the Spaniard, who had looked calm and confident in his first Grand Slam semi-final, was eventually brushed aside.”I had to dig deep. It’s the semi-finals and Roberto was not overwhelmed – he’s a very under-rated player,” Djokovic, 32, said. Tennis 10 Jul 2019 Clinical Djokovic destroys Goffin to reach semislast_img read more