An Oxford-led team of researchers has become the first to discover a genetic mutation which can lead to severe facial disfigurement.The mutation, known as ALX3, was discovered after researchers compared the DNA of individuals from seven families who all shared a similar facial malformation known as ‘frontorhiny’.Head researcher Professor Andrew Wilkie said, “This finding offers hope to those families considered to be at risk. By correctly diagnosing the condition in an adult, we can reassure them that their children are unlikely to be affected.”
Google+ IndianaLocalNews Facebook Facebook School bus and sheriff’s vehicle collide in Steuben County, two injured By Brian Davis – October 14, 2020 0 352 Google+ WhatsApp (95.3 MNC) A Steuben County Sheriff’s Deputy and a school bus driver for the Metropolitan School District of Steuben County were injured in a crash between a Sheriff’s Vehicle and a bus.Officials say the crash happened at about 2:40 PM Tuesday when a 2019 Ram Pickup Truck owned by the Steuben County Sheriff failed to stop for a Metropolitan School District bus that was crossing the railroad tracks on road 200 north.Both the deputy and bus driver suffered minor injuries.No children were on board the bus at the time of the crash. WhatsApp Twitter Twitter Pinterest Pinterest Previous articleGroups say Hoosiers with disabilities still face ballot barriersNext articleMan arrested for Marshall County stabbing Sunday Brian Davis
WrestleMania 35 takes place Sunday, April 7, at MetLife Stadium in East Rutherford, N.J., and will air live on the WWE Network and on pay-per-view. The biggest show of the year for wrestling fans will once again feature all of the typical WWE pageantry and big matches, including the first women’s main event in WrestleMania history.Below you’ll find everything you need to know about the annual extravaganza, including the full match card, WrestleMania facts for each participant, and the current betting odds. WrestleMania debutAsuka: WrestleMania 34 (2018Dana Brooke: WrestleMania 34 (2018)Mickie James: WrestleMania 22 (2006)Ruby Riott: WrestleMania 34 (2018)Liv Morgan: WrestleMania 34 (2018)Sarah Morgan: WrestleMania 34 (2018)Carmella: WrestleMania 33 (2017)Naomi: WrestleMania 30 (2014)Lana: WrestleMania 32 (2016)Mandy Rose: WrestleMania 35 (2019)Sonya Deville: WrestleMania 35 (2019)Zelina Vega: WrestleMania 35 (2019)Nikki Cross: WrestleMania 35 (2019)WrestleMania win-loss recordAsuka: 0-1Dana Brooke: 0-1Mickie James: 1-4Ruby Riott: 0-1Liv Morgan: 0-1Sarah Morgan: 0-1Carmella: 0-2Naomi: 2-2Lana: 0-2Mandy Rose: 0-1Sonya Deville: 0-1Zelina Vega: 0-0Nikki Cross: 0-0Gambling oddsAsuka: +250Dana Brooke: +2000Mickie James: +3300Ruby Riott: +2000Liv Morgan: +3300Sarah Morgan: +3300Carmella: +1000Naomi: +2000Lana: +3300Mandy Rose: +800Sonya Deville: +1200Zelina Vega: +2500Nikki Cross: +2000Shayna Baszler +1400Tenille Dashwood +3300 (Gambling odds are provided from BetOnline.ag)Join DAZN and watch more than 100 fight nights a year When is WrestleMania 35?WWE WrestleMania 35 will air live on Sunday, April 7, 2019. The pre-show will start at 5 p.m. with the main card beginning at 7 p.m. ET.Where will WrestleMania 2019 be held?MetLife Stadium in East Rutherford, N.J., is the site of WrestleMania 35. The home of the NFL’s Jets and Giants holds a capacity of 82,500. MetLife Stadium also hosted WrestleMania 29 in 2013. MORE WRESTLEMANIA:• 10 great moments that define WrestleMania like no other• The best WrestleMania entrances of all time, ranked• Ranking the 10 worst WrestleMania main event matches• Ranking WrestleMania’s top 10 matches all timeWrestleMania 35 match cardRonda Rousey vs. Charlotte Flair vs. Becky Lynch in a Triple Threat match for the “RAW” women’s championshipThis match is literally history in the making with the women earning the closing spot on the show. Rousey goes into the match as the “RAW” Women’s Champion and claiming that she is the “baddest woman on the planet”. But Becky Lynch is having none of that and, with the fans behind her, has risen to become the most interesting personality in the WWE. Now, Flair comes into the match as the “SmackDown” Women’s Champion, possibly adding another intriguing layer to the match depending on what titles will be up for grabs.WrestleMania debutRonda Rousey: WrestleMania 34 (2018)Charlotte Flair: WrestleMania 32 (2016)Becky Lynch: WrestleMania 32 (2016)WrestleMania win-loss recordRonda Rousey: 1-0Charlotte Flair: 2-0Becky Lynch: 0-2Gambling oddsRonda Rousey: +450Charlotte Flair: +300Becky Lynch: -350SN Q&A: Rob Van Dam talks return to Impact Wrestling, Vince McMahon, more Brock Lesnar vs. Seth Rollins for the WWE Universal championshipEver since Rollins suffered a serious knee injury in late 2015, he has been working his way back to the top of the WWE. Now he has his chance. With his Royal Rumble win in January, he earned a shot at the Universal championship and wasn’t deterred, even after Lesnar destroyed him with six F5s. All Rollins has to do to take the title is slay “The Beast”.WrestleMania debutBrock Lesnar: WrestleMania 19 (2003)Seth Rollins: WrestleMania 29 (2013)WrestleMania win-loss recordBrock Lesnar: 5-3Seth Rollins: 5-1Gambling oddsBrock Lesnar: +100Seth Rollins: -140Daniel Bryan vs. Kofi Kingston for the WWE ChampionshipKingston has been the model WWE employee for more than a decade but now he wants his opportunity to be WWE champion. Even after jumping through every hoop put in front of him, Mr. McMahon has pulled the rug out from him. But after his New Day brothers Big E and Xavier Woods won a tag team gauntlet, Kingston will finally get his shot at the gold on the biggest stage and the chance to prove he is more than a B+ player.WrestleMania debutDaniel Bryan: WrestleMania 27 (2011)Kofi Kingston: WrestleMania 24 (2008)WrestleMania win-loss recordDaniel Bryan: 5-2-1Kofi Kingston: 1-8Gambling oddsDaniel Bryan: +180Kofi Kingston: -270Triple H vs. Batista in a No Holds Barred match; if Triple H loses, he must retire as a wrestlerBatista has talked for years about having one last run in WWE, capping it off against Triple H at WrestleMania. It took him attacking Ric Flair on his 70th birthday to get Triple H’s attention and now the match is on with “The Game” putting his career on the line. This will be a fight between two Hall of Famers with the no holds barred stipulation.WrestleMania debutTriple H: WrestleMania 12 (1996)Batista: WrestleMania 20 (2004)WrestleMania win-loss recordTriple H: 9-13Batista: 3-3Gambling oddsTriple H: -400Batista: +250Roman Reigns vs. Drew McIntyreNow that Reigns is back with his leukemia in remission, he needed a big-name opponent to square off. It just so happened that McIntyre was also looking for a top star to square with on the big stage. The “Scottish Terminator” has been trying to take out every member of The Shield and has gotten in some good shots on Reigns so far. Now, the big athletic superstars will square off to see who can claim the yard.WrestleMania debutRoman Reigns: WrestleMania 29 (2013)Drew McIntyre: WrestleMania 26 (2010)WrestleMania win-loss recordRoman Reigns: 4-2Drew McIntyre: 1-3Gambling oddsRoman Reigns: -300Drew McIntyre: +200Bobby Lashley vs. Finn Balor for the intercontinental championshipThese two men have been intertwined for the past few months with Balor having a short run with the title before losing it to Lashley on an episode of “RAW” in mid-March. Balor later beat Lashley and Jinder Mahal in a handicapped match to earn a shot at the title as he looks to become a two-time I-C champion.WrestleMania debutBobby Lashley: WrestleMania 23 (2007)Finn Balor: WrestleMania 34 (2018)WrestleMania win-loss recordBobby Lashley: 1-0Finn Balor: 0-1Gambling oddsBobby Lashley: +350Finn Balor: -600Shane McMahon vs. The Miz in a Falls Count Anywhere matchThe unlikely team of McMahon and The Miz was working, so well in fact that they became the “SmackDown” tag team champions. They lost the titles to The Usos and then they failed to win them back at Fastlane, McMahon lost his mind and brutally beat down The Miz in front of his dad in his hometown of Cleveland. The Miz is hot for revenge and with this being a falls count anywhere match, the fight could go anywhere in the building and who knows what McMahon will be flying off of inside MetLife Stadium.WrestleMania debutShane McMahon: WrestleMania 15 (1999)The Miz: WrestleMania 25 (2009)WrestleMania win-loss recordShane McMahon: 3-2The Miz: 4-6Gambling oddsShane McMahon: +170The Miz: -250Randy Orton vs. AJ StylesThis has been slowly coming together over the past few months with each of them interrupting the other in backstage segments and then trading insults. Orton wasn’t too fond when Styles referred to the blue brand as “the place that AJ Styles built” considering he began his career in SmackDown back in 2002. We’ll see who has bragging rights when they go one-on-one.WrestleMania debutRandy Orton: WrestleMania 20 (2004)AJ Styles: WrestleMania 32 (2016)WrestleMania win-loss recordRandy Orton: 6-8AJ Styles: 2-1Gambling oddsRandy Orton: -165AJ Styles: +125Kurt Angle vs. Baron Corbin in Angle’s retirement matchAngle announced last month that he will end his Hall of Fame career at WrestleMania 35 and was given the opportunity to choose his opponent for his final match. It made sense that Angle would pick Corbin who took his spot as the “RAW” General Manager last year and has been a thorn in his side. However, that announcement has not been well-received by fans who wanted to see Angle face a bigger name in his sendoff match. That controversy continues making some wonder if there could be something else in the works come Sunday night.WrestleMania debutKurt Angle: WrestleMania 16 (2000)Baron Corbin: WrestleMania 32 (2016)WrestleMania win-loss recordKurt Angle: 4-4Baron Corbin: 1-2Gambling oddsKurt Angle: -250Baron Corbin: +170Samoa Joe vs. Rey Mysterio for the WWE United States championshipIt took a while but Joe finally won his first WWE title in early March when he defeated R-Truth, Andrade, and Mysterio to win the U.S. championship. He successfully defended it at Fastlane and Mysterio was named his WrestleMania opponent. If given enough time, this could be one of the better matches of the night. One other thing to look out for: Mysterio’s son Dominic, who is training to be a wrestler and has made some recent backstage TV appearances, will be sitting ringside.WrestleMania debutSamoa Joe: WrestleMania 35 (2019)Rey Mysterio: WrestleMania 19 (2003)WrestleMania win-loss recordSamoa Joe: 0-0Rey Mysterio: 7-4Gambling oddsSamoa Joe: -250Rey Mysterio: +170The Boss ‘n’ Hug Connection (Bayley and Sasha Banks) vs. The Divas of Doom (Beth Phoenix and Natalya) vs. The IIconics (Billie Kay and Peyton Royce) vs. Nia Jax and Tamina Snuka in a Fatal Four-Way match for the “RAW” women’s championshipBayley and Sasha haven’t been shy in saying that they’re the best team in the WWE and will take on all comers. They’ll have to do just that with these other three teams answering the call over the past few weeks leading up to the big event.WrestleMania debutBayley: WrestleMania 33 (2017)Sasha Banks: WrestleMania 32 (2016)Beth Phoenix: WrestleMania 24 (2008)Natalya: WrestleMania 25 (2009)Billie Kay: WrestleMania 35 (2019)Peyton Royce: WrestleMania 35 (2019)Nia Jax: WrestleMania 33 (2017)Tamina Snuka: WrestleMania 30 (2014)WrestleMania win-loss recordBayley: 1-1Sasha Banks: 0-2Beth Phoenix: 1-3Natalya: 1-4Billie Kay: 0-1Peyton Royce: 0-1Nia Jax: 1-1Tamina Snuka: 0-2Gambling oddsBoss ‘n’ Hug Connection: -260Beth Phoenix and Natalya: +500The IIconics: +250Nia Jax and Tamina: +1000Buddy Murphy vs. Tony Nese WWE Cruiserweight championshipNese earned his shot for the cruiserweight title after winning the #1 contender tournament on 205 Live, defeating Cedric Alexander in the finals. Now, he’ll get to take on his buddy, who also happens to be the champ. It’s somewhat of an unlikely match but Buddy Murphy has been tearing it up on the brand and this match shouldn’t be any different.WrestleMania debutBuddy Murphy: WrestleMania 35 (2019)Tony Nese: WrestleMania 35 (2019)WrestleMania win-loss recordBuddy Murphy: 0-0Tony Nese: 0-0Gambling oddsBuddy Murphy: -180Tony Nese: +140Andre the Giant Memorial Battle RoyalThe annual battle royal match honoring the late Andre the Giant will be held for the 6th consecutive year. There really isn’t much at stake here other than bragging rights and a huge trophy and the match is more of a way to get a bunch of other talent onto the show. The match has had its moments over the years including former Patriots’ star Rob Gronkowski getting involved several years back. Both Michael Che and Colin Jost of SNL fame will be participants and who knows what other surprises could be in store.WrestleMania debutBraun Strowman: WrestleMania 32 (2016)Michael Che: WrestleMania 35 (2019)Colin Jost: WrestleMania 35 (2019)Matt Hardy: WrestleMania 16 (2000)Jeff Hardy: WrestleMania 16 (2000)Titus O’Neil: WrestleMania 30 (2014)Curtis Axel: WrestleMania 30 (2014)Andrade: WrestleMania 35 (2019)Shelton Benjamin: WrestleMania 19 (2003)Ali: WrestleMania 35 (2019)Apollo Crews: WrestleMania 34 (2018)Tyler Breeze: WrestleMania 32 (2016)Jinder Mahal: WrestleMania 30 (2014)No Way Jose: WrestleMania 35 (2019)Bobby Roode: WrestleMania 34 (2018)Chad Gable: WrestleMania 33 (2017)Kalisto: WrestleMania 32 (2016)Gran Metalik: WrestleMania 35 (2019)Lince Dorado: WrestleMania 35 (2019)Bo Dallas: WrestleMania 31 (2015)Heath Slater: WrestleMania 27 (2011)Rhyno: WrestleMania 17 (2001)Viktor: WrestleMania 31 (2015)Konnor: WrestleMania 31 (2015)Luke Gallows: WrestleMania 26 (2010)Karl Anderson: WrestleMania 34 (2018)Otis: WrestleMania 35 (2019)Tucker: WrestleMania 35 (2019)EC3: WrestleMania 35 (2019)WrestleMania win-loss recordBraun Strowman: 1-1Michael Che: 0-0Colin Jost: 0-0Matt Hardy: 4-6Jeff Hardy: 1-5Titus O’Neil: 0-3Curtis Axel: 0-4Andrade: 0-0Shelton Benjamin: 1-7Ali: 0-0Apollo Crews: 0-1Tyler Breeze: 0-3Jinder Mahal: 1-2No Way Jose: 0-0Bobby Roode: 0-1Chad Gable: 0-2Kalisto: 1-1Gran Metalik: 0-0Lince Dorado: 0-0Bo Dallas: 0-4Heath Slater: 0-6Rhyno: 0-4Viktor: 0-4Konnor: 0-4Luke Gallows: 0-3Karl Anderson: 0-2Otis: 0-0Tucker: 0-0EC3: 0-0Gambling oddsBraun Strowman: +120Michael Che: +2500Colin Jost: +2500Matt Hardy: +5000Jeff Hardy: +4000Titus O’Neil: +5000Curtis Axel: N/AAndrade: +1200Shelton Benjamin: N/AAli: +1600Apollo Crews: +4000Tyler Breeze: N/AJinder Mahal: N/ANo Way Jose: +2500Bobby Roode: +3300Chad Gable: +5000Kalisto: N/AGran Metalik: N/ALince Dorado: N/ABo Dallas: N/AHeath Slater: N/ARhyno: N/AViktor: N/AKonnor: N/ALuke Gallows: N/AKarl Anderson: N/AOtis: N/ATucker: N/AEC3: +2500Rob Gronkowski: +1000Lars Sullivan: +1600Curt Hawkins: +1000Velveteen Dream: +2000Harper: +2000Bray Wyatt: +2500Adam Cole: +4000Mojo Rawley: +2500Pete Dunne: +4000Hulk Hogan: +5000Elias: +5000Rowan: +5000Conor McGregor: +5000Kane: +4000Second Annual WrestleMania Women’s Battle RoyalThis match debuted last year in New Orleans with Naomi outlasting the rest of her female superstars to get the win. With Asuka losing the “SmackDown” women’s championship, she’ll have to settle for this match and we’ll see who else enters the fray over this last week leading up to the show.